Evidence for non-independent gating of P2X2 receptors expressed in Xenopusoocytes

BMC Neuroscience

Table 1 Single channel parameters estimated from all-points amplitude histograms

[ATP], (μM)	i, (pA)	σ_ex, (pA)	σ_ex/i,
5	2.80 ± 0.1	2.54 ± 0.14	0.90
10	3.36 ± 0.05	2.42 ± 0.09	0.71
15	3.58 ± 0.03	2.31 ± 0.05	0.64
20	3.61 ± 0.03	2.38 ± 0.05	0.66
30	3.54 ± 0.02	2.31 ± 0.04	0.66
50	3.38 ± 0.03	2.30 ± 0.04	0.68
100	3.60 ± 0.02	2.35 ± 0.04	0.65

Note: The results were obtained from the all-points histograms in Figure 5. The relative excess open channel noises of single channel current are similar except the current activated by 5 μM ATP. This outliner is due to the low open probability that make the fitting of Gaussian distribution unreliable.

ISSN: 1471-2202