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Figure 2 | BMC Neuroscience

Figure 2

From: Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death

Figure 2

Glutamate-induced toxicity in mouse hippocampal HT22 cells as assessed by phase contrast microscopy (200×). HT22 cells were cultured and treated with glutamate alone or in the presence of estrogens for 8 to 18 h. Degenerated cells are depicted by arrows. A = Untreated control cells; B = 10 mM glutamate; C = 10 mM glutamate + 10 μM Δ8,17β-E2; D = 8 mM glutamate + 10 μM 17β-E2; E = cells treated with 5 mM glutamate for 18 h; F = 5 mM glutamate + 10 μM 17β-E2 for 18 h.

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BMC Neuroscience

ISSN: 1471-2202

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