Skip to main content
Figure 5 | BMC Neuroscience

Figure 5

From: The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins

Figure 5

Fas expression is associated with p53 activation. (A) Sample flow cytometric scatter-plot showing a strong positive association between the intensity of p53 phosphorylation (pp53) and cell surface Fas expression in primary cortical precursors. Asterisk indicates statistical significance of Pearson's product moment correlation (inset). (B,C) Sample western blot (B) and quantitative densitometric analysis of Fas expression in conditionally immortalized CHB50 cerebral cortical neuroblasts under -p53 conditions (+tsTA/-pp53) and under +p53 conditions (-tsTA/+pp53) for 24 or 48 hours.

Back to article page

BMC Neuroscience

ISSN: 1471-2202

Contact us