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Figure 8 | BMC Neuroscience

Figure 8

From: The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins

Figure 8

Densitometric analyses of western immunoblots of samples obtained from conditionally immortalized CHB50 cortical neuroblasts cultured for 24 or 72 hours following p53 induction (-tsTA/+pp53 condition). During this duration, cultures were maintained either under control conditions or were exposed to E2 alone or E2 with tamoxifen. E2 induced a significant decrease in Fas that was not reversed by concurrent exposure to tamoxifen. Asterisks indicate statistical significance at p < 0.05.

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