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Figure 4 | BMC Neuroscience

Figure 4

From: Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

Figure 4

Cre-mediated recombination following injection of LV-Cre-EGFP (A-C) and a mixture of AAV-Cre and AAV-GFP recombinant viruses (AAV-Cre/AAV-GFP mixture) (D-F) into the neocortex and hippocampus of Rosa26 reporter mice. Expression of β-galactosidase, indicating Cre-mediated excision of the loxP flanked stop signal, was detected by the X-gal staining. β-galactosidase activity was prominent in the dentate gyrus of animals at all postinjection intervals (arrows in A-F). Scale bars A= 100 μm (applies also to B-F).

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BMC Neuroscience

ISSN: 1471-2202

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