Figure 3From: Effects of prostaglandin E2 on the electrical properties of thermally classified neurons in the ventromedial preoptic area of the rat hypothalamusThe effects of PGE 2 on the input resistance of a VMPO temperature insensitive neuron (A) and a VMPO warm sensitive neuron (B). For each, changes in membrane potential are plotted in response to a series of hyperpolarizing current pulses (-10 to -100 pA, 200 ms), during baseline conditions (●), perfusion with PGE2 (▲), and after PGE2 has been washed out of the chamber (■). For the temperature insensitive neuron in A (m = 0.05), input resistance decreased from a baseline of 406.33 MΩ, to 332.40 MΩ during perfusion with PGE2. After PGE2 had been washed out of the chamber, input resistance increased to 372.32 MΩ. For the warm sensitive neuron in B (m = 1.30), input resistance decreased from a baseline of 388.00 MΩ, to 244.86 MΩ during perfusion with PGE2. After PGE2 had been washed out of the chamber, input resistance increased to 327.63 MΩ.Back to article page