The role of the cytoskeleton in cell body enlargement, increased nuclear eccentricity and chromatolysis in axotomized spinal motor neurons

Table 4 Newly synthesized protein in isolated cell body cytoskeletons before and after axotomy.

	³H-leucine-labeled protein (cpm/cell body)
	Normal	Axotomized
Unextracted cells	36.0 ± 15.4	210.6 ± 25.7**
Extracted Cells	19.8 ± 11.1†	114.8 ± 29.1**††
E/U × 100^a	55.0%	54.5%

Mean cpm ± S.D. for cell bodies and their cytoskeletons isolated from labeled spinal cords of normal and 16-day axotomized frogs in 3 experiments.
^a E/U × 100 = percent new protein allocated to the cell body cytoskeleton
** p < 0.01: axotomized vs. normal, Student's unpaired t-test
† p < 0.05; †† p < 0.01: extracted vs. unextracted, Students paired t-test

ISSN: 1471-2202