Figure 4
From: Astrocyte reactivity to Fas activation is attenuated in TIMP-1 deficient mice, an in vitrostudy
Release of MCP-1 by WT and KO astrocytes was measured in supernatants by ELISA. MCP-1 release was up-regulated by TNF-α in astrocytes from WT and KO mice, whereas Fas activation increased MCP-1 release only in WT astrocytes. Values represent the mean +/- s.e.m. of at least three independent experiments. Statistical differences were determined by Student's t-test when comparing treatments to control cells (* p < 0.05).