From: Convulsant bicuculline modifies CNS muscarinic receptor affinity
Area | Condition | Kd (pM) | Δ (%) | Bmax (pmol.mg prot-1) | NH |
---|---|---|---|---|---|
Cerebellum | Control | 200.1 ± 7.1 |  | 0.35 ± 0.01 | 1.00 ± 0.01 |
 | Convulsive | 133.3 ± 7.5*** | - 33 | 0.42 ± 0.07 | 1.05 ± 0.02 |
Hippocampus | Control | 108.8 ± 2.7 |  | 1.75 ± 0.08 | 1.01 ± 0.06 |
 | Convulsive | 185.6 ± 3.9*** | + 85 | 1.72 ± 0.11 | 0.98 ± 0.02 |