Figure 2From: Place preference induced by nucleus accumbens amphetamine is impaired by local blockade of Group II metabotropic glutamate receptors in ratsTime (+ SEM) spent on the drug-paired side during the 15 min pre-exposure and the test sessions. Testing occurred after conditioning with amphetamine (20 μg) and the Group II mGluR antagonist EGLU (0.0–0.8 μg) administered locally into NAc (bilaterally in 0.5 μl vehicle). One group received 0.01 μg EGLU alone, i.e. no amphetamine was administered before conditioning sessions. See Table 1 for number of animals per group. aSignificantly higher than time spent on drug-paired side on test day for rats receiving 0.4 μg of EGLU. bSignificantly higher than time spent on drug-paired side on test day for rats receiving 0.01–0.8 μg of EGLU.Back to article page