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Figure 3 | BMC Neuroscience

Figure 3

From: Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice

Figure 3

Resistance to optic nerve crush is heritable. Histographs showing the distribution of cell loss in 5 different populations of mice. (A) DBA/2J parental strain. (B) BALB/cByJ parental strain. (C) F1 generation of mice from DBA/2J and BALB/cByJ parents. These offspring inherit a level of resistance comparable to the DBA/2J parental strain. (D) N2 backcross generation of mice (F1 mice crossed with BALB/cByJ mice). These mice exhibit a shift toward the BALB/cByJ pattern of lowered resistance to optic nerve crush. (E) F2 generation of mice (F1 intercross). These mice exhibit an intermediate pattern of resistance.

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