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Table 1 Plasma corticosterone level [ng/ml] of adult tamoxifen-treated GRCaMKCreERT2 mice at diurnal trough

From: Inducible gene inactivation in neurons of the adult mouse forebrain

line

control

mutant

vs. one copy

vs. two copies

one copy

13 ± 5

39 ± 8*

  
 

n = 7

n = 9

  

two copies

8 ± 1

100 ± 20*

p < 0.05

 
 

n = 7

n = 9

  

four copies

15 ± 6

108 ± 19*

p < 0.05

p = 0.75

 

n = 5

n = 5

  
  1. control = GRflox/flox, mutant = GRflox/flox/CaMKCreERT2 transgene
  2. * p < 0.05, control versus mutant