Figure 10

NFV induces the expression of NICD gene targets in CEC. Western analyses of A) NFκB (*p ≤ 0.005, ** p ≤ 0.05) after 6, 24 and 48 h exposure to 5 μM saquinavir (S), indinavir (I), nelfinavir (N), ritonavir (R), Vitamin E (VE), or VE/N, B) MMP2 (*p ≤ 0.01) and D) HES-1 protein levels after 48 h exposure to 5 μM saquinavir (S), indinavir (I), nelfinavir (N), ritonavir (R), with and without vitamin E (VE) pre-treatment. P values determined by one way ANOVA with Dunnett's post hoc tests when compared to control. Graphs reflect results from three or more separate experiments.