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Figure 4 | BMC Neuroscience

Figure 4

From: Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivation

Figure 4

Three-dimensional representations of DA modulatory landscapes with (B) and without (A, C, and D) chandelier cells. The strength of the inhibition by other GABAergic interneurons are also varied (A: 1.0, B: 1.0, C: 0.95, and D: 1.06). Note that the onset of the H mode is very quick (less than 100 ms), whereas the inverted-U mode profiles are very slow to evolve. Even at t = 1000 ms, the profiles of the inverted-U mode have not reached the equilibrium states. The profiles at equilibrium are shown in Figure 3.

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