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Table 3 Temporal profile of differentially expressed genes in cerebellum and cerebrum of prosaposin deficient mouse models

From: Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice

Genotypes

Tissues

Expression

Number of differentially expressed genes

   

0 day

10 days

20 days

25 days

4 weeks

12 weeks

18 weeks

PS-/-

Cerebellum

up

151

97

212

213

   
  

down

58

43

83

83

   
  

subtotal

209

140

295

296

   
 

Cerebrum

up

134

70

250

288

   
  

down

22

52

66

64

   
  

subtotal

156

122

316

352

   

PS-NA

Cerebellum

up

134

   

238

265

390

  

down

164

   

99

87

124

  

subtotal

298

   

337

352

514

 

Cerebrum

up

54

   

100

212

232

  

down

61

   

59

48

22

  

subtotal

115

   

159

260

254

4L/PS-NA

Cerebellum

up

    

436

868

831

  

down

    

270

428

313

  

subtotal

    

706

1296

1144

 

Cerebrum

up

    

216

347

341

  

down

    

88

98

67

  

subtotal

    

304

445

408