Target Epitope | Antibody (Supplier) | Reference |
---|---|---|
hAPP | Rabbit monoclonal clone Y188 | - |
Amyloid precursor protein A4, corresponding to the NPXY motif of hAPP | (Abcam) | Â |
hAPP/Aβ | Mouse monoclonal clone 6E10 | Götz J, et al. [70] |
Aβ amino acid residues 1–16; also cross-reacts with hAPP | (Signet) | Hock C, et al. [71] |
 |  | Oddo S, et al. [72] |
hAβ 1–42 (extracellular) C-terminus of Aβ 1–42 | Mouse monoclonal clone 12F4 | Parvathy, S., et al. [73] |
 | (Covance/Signet) |  |
hAβ 1–42 (intracellular) C-terminus of Aβ 1–42 | Rabbit polyclonal anti Aβ 1–42 | D'Andrea, et al [27] |
 | (Biosource/Invitrogen) |  |
hTau | Mouse monoclonal HT7 | Oddo et al [18] |
Human Tau amino acid residues 159–163 | (Pierce) | Mercken M et al [74] |
Phosphorylated Tau | Mouse monoclonal AT180 | Greenberg and Davies [39] |
Human Tau phosphorylated residue Thr231 | (Pierce) | Oddo S et al. [18] |
Paired Helical Filaments | Monoclonal mouse anti-PHF-1 | Ksiezak-Reding, et al. [37] |
Human Tau phosphorylated on amino acid residues Ser396 and Ser404 associated with paired helical filaments | (Dr. Peter Davies, Albert Einstein School of Medicine) | Clinton, et al. [68] |
F4/80 | Rat anti mouse F4/80 | Janelsins et al. [52] |
 | (AbD Serotec) |  |
Cell surface glycoprotein on mature macrophages that is a member of the EGF-TM7 family | Â | Â |
GFAP | Rabbit polyclonal anti-GFAP | Shaftel S, et al. [75] |
Cell surface marker (glial fibrillary acidic protein) for mature astrocytes | (Dako Cytomation) | Â |