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Table 1 Sojourn times and Normalized Transition Rates (NTR) in the onset phase

From: Chronic escitalopram treatment attenuated the accelerated rapid eye movement sleep transitions after selective rapid eye movement sleep deprivation: a model-based analysis using Markov chains

Onset phase (starting at light onset; 0-2000 s)

Group

WAKE

SLEEP

 

Sojourn time (s)

L

U

Sojourn time (s)

L

U

RD-SSRI

212.102

155.104

290.046

25.467

16.864

38.460

HC-SSRI

254.713

186.264

348.315

14.176 *

9.387

21.408

RD-VEH

374.026 *

264.968

527.973

21.609

13.941

33.493

HC-VEH

174.131

127.337

238.122

35.239

23.334

53.216

 

WAKE→SLEEP

SLEEP→WAKE

 

NTR

L

U

NTR

L

U

RD-SSRI

0.821

0.587

1.147

1.384

0.958

1.999

HC-SSRI

0.684 *

0.489

0.956

2.486 *

1.791

3.450

RD-VEH

0.465 *

0.323

0.670

1.631 *

1.135

2.343

  1. Sojourn time: the estimated mean of the average time span of an event;
  2. Normalized Transition Rate (NTR): relative transition rate compared to the HC-VEH group (NTR of the HC-VEH group is 1);
  3. * p < 0.05, significant effect compared to the HC-VEH group;
  4. L and U: lower and the upper limits of the corresponding 95% confidence interval, respectively;
  5. Normalized Transition Rate (NTR): relative transition rate compared to the HC-VEH group (NTR of the HC-VEH group is 1);
  6. Groups: home cage plus chronic vehicle treatment (HC-VEH); home cage plus chronic escitalopram treatment (HC-SSRI); REM sleep deprivation plus chronic vehicle treatment (RD-VEH); REM sleep deprivation plus chronic escitalopram treatment (RD-SSRI).