Cognitive-behavioral phenotypes of Williams syndrome are associated with genetic variation in the GTF2I gene, in a healthy population

Table 2 P-values from ANOVAs comparing mean values of psychological variables between genotypes

	Genetic marker, model
	rs4717907			rs13227433
Psychological variable	CODOM	DOM	REC	CODOM	DOM	REC
AQ-Social	0.28	0.98	0.13	0.14	0.57	0.10
AQ-Communication	0.12	0.15	0.06	0.08	0.24	0.03*
SPQ-Social Anxiety	0.09	0.04*	0.94	0.09	0.04*	0.91
Williams syndrome profile score	0.0053**	0.0017**	0.08	0.0069**	0.0033*	0.04*
AQ-Total	0.44	0.79	0.20	0.14	0.80	0.08
SPQ-Total	0.36	0.58	0.29	0.64	0.90	0.39

CODOM refers to codominant model (ANOVA with 2 df), DOM and REC refer to models that pool heterozygotes with one of the homozygotes (1 df).
Boldface highlights statistical significance, with * for P < 0.05 and ** for P < 0.01.

ISSN: 1471-2202