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Table 1 Top 15 differently methylated sites in weight category and the STK33 rs4929949 polymorphism; Weight category

From: Implication of coronin 7 in body weight regulation in humans, mice and flies

Gene

Entrez gene ID

Genomic position of the probe/island (hg19)

HIL class

Genomic location of the closest TSS (hg19)

Coefficient

Raw p-value

Adjusted p-value

CKAP2L

150468

chr2:113521873

HC

113522253

0,159

8,46E-06

8,85E-02

DCHS1

8642

chr11:6676514

HC

6677073

āˆ’0,221

3,92E-05

2,05E-01

ZNF35

7584

chr3_IC:44689963-44690779

IC

44690232

āˆ’0,14

7,16E-05

2,22E-01

HAP1

9001

chr17:39890959

HC

39890897

āˆ’0,159

8,47E-05

2,22E-01

PIN1

5300

chr19:9945603

HC

9945882

0,152

0,000108

0,226

SERF2

10169

HCshore:44083868ā€“44085029; ICshore:44084026-44085439

HC

44084574

0,128

0,00015

0,26

CERCAM

51148

chr9_HCshore:131182042ā€“131183333; chr9_ICshore:131181735-131183621

HC

131182465

āˆ’0,157

0,000189

0,26

TEX10

54881

chr9:103115131

HC

103115258

āˆ’0,19

0,000199

0,26

CORO7-PAM16

100529144

chr16:4466649

HC

4466961

āˆ’0,137

0,000255

0,272

NME1-NME2

654364

chr17_HCshore:49230603ā€“49231546; chr17_ICshore:49230561-49231528

HC

49230896

āˆ’0,109

0,00026

0,272

ARHGDIB

397

chr12:15114393

IC

15114561

āˆ’0,191

0,000314

0,298

KLK10

5655

chr19_HCshore:51520036ā€“51521297; chr19_ICshore:51519915-51521326

HC

51522953

āˆ’0,142

0,000439

0,383

ZNF215

7762

chr11:6947572

HC

6947653

āˆ’0,164

0,000729

0,549

HEATR6

63897

chr17:58156231

HC

58156291

0,132

0,000754

0,549

SLC22A18

5002

.;chr11_IC:2923161-2923957

IC

2923511

āˆ’0,134

0,000965

0,549

  1. Abbreviations: high-density CpG island (HC), intermediate-density CpG island (IC), region of intermediate-density CpG island that borders HCs (ICshore).