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Figure 6 | BMC Neuroscience

Figure 6

From: Simulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times faster

Figure 6

Removal of the BK current (to simulate a genetic knockout of the BK channel) switches both the full and reduced Purkinje neuron models into depolarisation block quiescence. A, Membrane potential at the soma of the 2 compartment model. B, Membrane potential at the dendrite of the 2 compartment model. C, Membrane potential at the soma of the 1089 compartment model. D, Membrane potential at the dendrite of the 1089 compartment model (spiny compartment 1001).

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BMC Neuroscience

ISSN: 1471-2202

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