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Figure 7 | BMC Neuroscience

Figure 7

From: Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels

Figure 7

The disruption of SLO-1/BK localization in unc-2 mutants is caused by altered CTN-1/α-catulin localization. (A) CTN-1 localization in wild-type and unc-2 mutant animals. The number of GFP::CTN-1 puncta was increased in unc-2 mutants compared with wild-type animals. The data are presented as the mean ± SEM and analyzed by two-tailed Student’s t-test (wild-type, n = 28; unc-2, n = 25; ***p < 0.001). (B) DYB-1 localization in wild-type and unc-2 mutant animals. The number of GFP::DYB-1 puncta was slightly increased in unc-2 mutants compared with wild-type animals. The data are presented as mean ± SEM and analyzed by two-tailed Student’s t-test (wild-type, n = 46; unc-2, n = 18; *p < 0.05). The scale bar represents 5 μm.

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BMC Neuroscience

ISSN: 1471-2202

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