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Table 4 Fatty acid composition of CD4+ T lymphocytes

From: A lipidomic approach to the study of human CD4+ T lymphocytes in multiple sclerosis

Fatty acids

HC

MS

14:0

1.5 ± 0.6

1.9 ± 0.7

16:0

34.3 ± 1.2

31.8 ± 2.0

16:1

0.2 ± 0.08

0.3 ± 0.09

18:0

57.2 ± 1.2

54.2 ± 4.0

18:1n-9

3.1 ± 0.5

5.6 ± 1.7*

18:1n-11

0.7 ± 0.06

0.9 ± 0.08**

18:2n-6

1.4 ± 0.2

2.0 ± 0.7

18:3n-3

0.5 ± 0.03

0.3 ± 0.01**

20:4n-6

1.5 ± 0.1

4.4 ± 0.2**

Σ SFA

92.9 ± 0.6

86.9 ± 4.3***

Σ MUFA

3.3 ± 0.2

5.8 ± 1.7***

Σ PUFA

3.3 ± 0.4

6.7 ± 0.9**

Total n-6

2.8 ± 0.9

6.4 ± 0.3**

SFA/PUFA

14.4 ± 1.7

7.9 ± 3.8***

UI

13.7 ± 3.2

29.1 ± 11.6***

  1. Fatty acids were obtained from whole CD4+ T lymphocytes as reported in the “Methods” section. Values are expressed as percentage of total fatty acids.
  2. MUFA monounsaturated fatty acids, PUFA polyunsaturated fatty acids, SFA saturated fatty acids, UI Unsaturation index.
  3. Values are given as mean ± SD.
  4. * P < 0.05; ** P < 0.01; *** P < 0.001.