Fig. 1From: Neuronal response in Alzheimer’s and Parkinson’s disease: the effect of toxic proteins on intracellular pathwaysCellular trafficking of APP and Aβ. APP cleavage to peptides occurs both in lysosomes after its endocytosis and at the surface of cell membrane. The proteolysis products accumulate intracellularly or are released into extracellular spaceBack to article page