Fig. 6From: Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult ratsScutellarin enhanced Notch-1expression in astrocytes after MCAO. Notch-1 expression is negligible in astrocytes in the sham (A1–3). Its expression (red) was moderately induced by MCAO in GFAP positive astrocytes (green) at 7 (B1–3) and 14 days (D1–3). However, Notch-1 expression was markedly increased in hypertrophic astrocytes in scutellarin treated MCAO rats (C1–3, E1–3) in comparison with the matching controls (B1–3, D1–3). Scale bars: 50 µm. DAPI-blue Back to article page