Fig. 9From: Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult ratsScutellarin enhanced nestin expression in astrocytes after MCAO. Nestin expression is undetected in astrocytes in the sham (A1–3). It (red) was moderately induced in GFAP positive astrocytes (green) in MCAO rats at 7 (B1–3) but declined at 14 days (D1–3). However, nestin expression was markedly increased in hypertrophic astrocytes in scutellarin treated MCAO rats at 7 (C1–3) and 14 days (E1–3) in comparison to the matching control groups (B1–3, D1–3). Scale bars: 50 µm. DAPI-blue Back to article page