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Fig. 2 | BMC Neuroscience

Fig. 2

From: The anterior insula and anterior cingulate cortex are associated with avoidance of dental treatment based on prior experience of treatment in healthy adults

Fig. 2

a The ratings of elicited fear were significantly correlated with the MDAS score and avoidance ratings based on experience. No significant correlation was found between the ratings of elicited fear and the avoidance ratings based on imagination. b Results of the ROI-based analysis. The anterior insula (aINS) and the dorsal anterior cingulate cortex (dACC) were selected as the regions of interest (ROIs) (the upper panel). The REXP task showed an increased activation in the right aINS and the bilateral dACC (the middle panel). The COUNT task showed an increased activation in the bilateral dACC (the lower panel). A cluster was considered statistically significant by small volume-correction based on the pre-defined ROIs (p < 0.05 corrected for family-wise error). c The ratings of experience-based avoidance were significantly correlated with the activation in the right aINS, the right dACC and the left dACC during the re-experience task

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