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Fig. 5 | BMC Neuroscience

Fig. 5

From: The preventive effect of resiniferatoxin on the development of cold hypersensitivity induced by spinal nerve ligation: involvement of TRPM8

Fig. 5

Effect of resiniferatoxin (RTX) pretreatment on transient receptor potential ankyrin type 1 (TRPA1) expression. Perineural administration with vehicle or RTX (0 or 1 µg) was performed prior to spinal nerve ligation (SNL). To evaluate the protein expression level of TRPA1 located in the dorsal root ganglion (DRG), the left L5 and L6 DRG were isolated 4 weeks after SNL. Western blot analysis was performed using 40 μg of total protein extracted from the isolated DRG (a). The specific signal for TRPA1 was quantified and plotted (b). β-actin was used as internal loading control

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