Abnormal white matter integrity in rapists as indicated by diffusion tensor imaging

Chen, Chiao-Yun; Raine, Adrian; Chou, Kun-Hsien; Chen, I-Yun; Hung, Daisy; Lin, Ching-Po

doi:10.1186/s12868-016-0278-3

BMC Neuroscience

Table 1 Brain regions showing significant differences between rapist and control subjects, illustrating clusters in which rapists had reduced and increased white matter fractional anisotropy compared with control subjects

From: Abnormal white matter integrity in rapists as indicated by diffusion tensor imaging

Cluster size (mm³)	MNI coordinates (mm)			Anatomical location		FA (Mean ± SD)		T score	p value	Cohen’s d
	x	y	z	White matter tract	Brain region	Control	Offender
Decreased FA in sex offenders versus controls
18	−35	−82	16	Inferior fronto-occipital fasciculus	Lateral occipital lobe, Middle occipital gyrus	0.42 ± 0.06	0.32 ± 0.03	5.55	0.0000	2.11
13	21	−43	0	Posterior cingulum	Parahippocampul gyrus	0.59 ± 0.05	0.50 ± 0.04	5.05	0.0001	1.99
10	52	−39	23	Superior longitudinal fasciculus	Inferior parietal lobule, or Supramarginal gyrus	0.54 ± 0.05	0.45 ± 0.05	4.26	0.0001	1.80
10	25	−35	−10	Posterior cingulum	Parahippocampul gyrus	0.60 ± 0.07	0.52 ± 0.05	3.39	0.0071	1.32
Increased FA in sex offenders versus controls
29	−16	33	11	Genu		0.55 ± 0.05	0.63 ± 0.06	4.08	0.0001	1.45
17	12	8	1	Internal capsule (anterior thalamic radiation)	Caudate	0.62 ± 0.05	0.71 ± 0.04	4.45	0.0002	1.99
16	−25	−69	26		Lateral occipital lobe (superior division)	0.48 ± 0.05	0.56 ± 0.05	4.11	0.0002	1.60
16	18	−10	−3	Poterior limb of internal capsule	Globus pallidus	0.70 ± 0.05	0.76 ± 0.04	4.16	0.0003	1.33
14	24	−46	3	Posterior cingulate	Posterior cingulate	0.34 ± 0.09	0.46 ± 0.07	3.88	0.0028	1.49
14	−6	51	−18	Forceps minor	Medial frontal pole	0.23 ± 0.03	0.32 ± 0.07	4.06	0.0001	1.67
12	−7	−81	29	Forceps major	Cunerus	0.24 ± 0.04	0.33 ± 0.06	4.47	0.0002	1.77
11	42	−51	37	Superior longitudinal fasciculus	Supramarginal, or Angular gyrus	0.38 ± 0.09	0.51 ± 0.07	4.18	0.0006	1.61
10	−13	0	4	Internal capsule (anterior thalamic radiation)	Caudate	0.63 ± 0.05	0.71 ± 0.06	3.83	0.0025	1.45
10	−11	−5	−10	Posterior limb of internal capsule	Lower thalamus	0.69 ± 0.04	0.76 ± 0.05	3.37	0.0013	1.55

Covariate: age

Back to article page

ISSN: 1471-2202

Contact us

General enquiries: journalsubmissions@springernature.com