Skip to main content
Fig. 1 | BMC Neuroscience

Fig. 1

From: Genotypic differences in intruder-evoked immediate early gene activation in male, but not female, vasopressin 1b receptor knockout mice

Fig. 1

Mean number of EGR-1 immunopositive cells/mm2 in a female vasopressin 1b receptor wild type (Avpr1b +/+) and knockout (Avpr1b −/−) (n = 5 both groups) mice following a maternal aggression test and b male Avpr1b +/+ (n = 12) and −/− (n = 10) mice following a resident intruder test. In females, there were no genotypic differences in any of the brain areas measured. In males, there were genotypic differences in the ventral bed nucleus of the stria terminalis (BNSTV) (F(1,20) = 6.89, p = 0.016) and anterior hypothalamic area (AHA) (F(1,18) = 8.46, p = 0.009); with Avpr1b −/− males having fewer EGR-1 immunopositive cells/mm2 than wild type controls. LSD dorsal lateral septum, LSV ventral lateral septum, BNSTD dorsal bed nucleus of the stria terminalis, MPOA medial preoptic area, PVN paraventricular nucleus, MeA medial amygdala, CA2 CA2 region of the hippocampus. Asterisks indicates a p value of less than 0.05

Back to article page