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Fig. 5 | BMC Neuroscience

Fig. 5

From: CX3C chemokine receptor 1 deficiency modulates microglia morphology but does not affect lesion size and short-term deficits after experimental stroke

Fig. 5

Functional outcome and lesion volumes after tMCAO. a Representative coronal sections from a wildtype (wt) and a CX3CR1 deficient (ko) mouse at day 7 following tMCAO. The encircled brain regions (contralateral hemisphere and non-injured part of the ischemic hemisphere) were used for lesion volume calculations. b Infarct volumes on day 7 and day 14 in wildtype (wt), heterozygous (hz) and CX3CR1 deficient mice (ko). Data are presented as mean ± SD. One-way analysis of variance. No statistical difference has been obtained at 7 days (p = 0.30) and 14 days (p = 0.61), respectively. c Composite neuroscore obtained on day 1 after tMCAO from wildtype (wt; n = 12), heterozygous (hz; n = 11) and CX3CR1 deficient mice (ko; n = 14). Scores are presented as medians with the 1st and 3rd quartile and whiskers. No statistical difference was found between the experimental groups (Kruskal–Wallis, p = 0.82)

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