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Fig. 2 | BMC Neuroscience

Fig. 2

From: Neural hyperactivity in the amygdala induced by chronic treatment of rats with analgesics may elucidate the mechanisms underlying psychiatric comorbidities associated with medication-overuse headache

Fig. 2

Representative traces of action potentials from neurons in the lateral central nucleus of the right amygdala (CeL) from rats chronically treated with the analgesics, and from saline-treated control rats. a Control, b acetaminophen, and c aspirin. The location of recorded neurons is shown in the inset. The bar graph compares the resting membrane potential, action-potential threshold, and ratio of rapid depolarization time and signal amplitude (mean ± SD of 10 animals). The threshold for action-potential generation in CeL neurons from rats chronically treated with aspirin or acetaminophen was more negative than that in control neurons from saline-treated rats. *P < 0.05, one-way ANOVA followed by a Dunnett test

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BMC Neuroscience

ISSN: 1471-2202

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