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Fig. 4 | BMC Neuroscience

Fig. 4

From: Neural hyperactivity in the amygdala induced by chronic treatment of rats with analgesics may elucidate the mechanisms underlying psychiatric comorbidities associated with medication-overuse headache

Fig. 4

Cortical spreading depression-evoked Fos-immunoreactive neurons in the trigeminal nucleus caudalis of rats chronically treated with acetaminophen or aspirin, and normal saline-treated control rats (scale bar 100 μm). The graph presents a statistical analysis of Fos-immunoreactive neurons (mean ± SD of counts per slide from 10 rats). *P < 0.05 compared with saline-treated control rats, one-way ANOVA followed by a Dunnett test. P < 0.05 between aspirin and acetaminophen treated rats, one-way ANOVA followed by a Dunnett test

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