Fig. 2

CBF information throughout the modeling of focal cerebral ischemia in the conscious (n = 11) and the anesthetic (n = 11) groups. a Representative LSI CBF images of rats from both groups. Images were acquired 15 min after illumination initiation. White dashed lines enclose the core CBF₅₀, i.e., more than 80% pixels of CBF₅₀ are within this area; while black dashed lines indicate the focus of the 532 nm light illumination applied in modeling of focal ischemia. Scale bar 1 mm. b The changes of CBF₅₀ throughout the stroke modeling in each group, showing a larger CBF reduction area in the conscious group after 8 min illumination. c The changes of CBF₊ showing a larger area with enhanced CBF in the anesthetic group during modeling. *P < 0.05