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Table 1 Features selected for the Infarct Evolution Classifier, and the metabolites tentatively assigned to those features

From: Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke

Feature selection order number

Feature chemical shift (ppm)

Assigned metabolite

Non-infarcted parenchyma*

Acute phase post-stroke*

Subacute phase post-stroke*

p value

1

1.33

Lac + ML(–CH2)

2.78 (2.38–3.21)

7.39 (6.67–8.90)

19.88 (10.38–22.11)

p < 0.01

2

3.05

TCr

3.83 (3.42–4.18)

1.96 (1.63–2.36)

2.01 (1.62–2.31)

p < 0.01

3

0.85

ML(–CH3)

3.32 (3.09–3.95)

3.02 (2.33–4.27)

12.30 (8.39–15.52)

p < 0.01

  1. * Median (interquartile range) of UL2CA normalized peak height values for each feature in the training set
  2. p value resulting from the Kruskall–Wallis test of the comparison of the selected feature among the three classes of the training set