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Fig. 1 | BMC Neuroscience

Fig. 1

From: Application of hairless mouse strain to bioluminescence imaging of Arc expression in mouse brain

Fig. 1

Comparison of pigmentation of head between C57BL/6 and Arc-Luc Tg HL mouse strains. a Dorsal views of head of C57BL/6 (upper panels) and Arc-Luc Tg HL (lower panels) mice at 4 (left panels) and 8 weeks of age (right panels). The photographs of the C57BL/6 mouse were taken after depilation. The C57BL/6 mouse at 8 weeks of age (upper right panel) and the Arc-Luc Tg HL mouse at both ages (lower left and right panels) are examples of suitable samples for BLI because of little pigmentation. The C57BL/6 mouse at 4 weeks of age (upper left) is an example of an unsuitable sample for BLI with skin pigmentation enclosed in a white dotted circle. Scale bar 10 mm. b Expression of IEGs in C57BL/6 and Arc-Luc Tg HL mice. Total RNA was extracted from the hippocampus 30 min after KA injection (n = 3, respectively). The changes in Arc, Egr-1, and c-fos expression levels were determined by quantitative RT-PCR analysis. The data represent mean ± SD

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