Fig. 4
From: Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice
Expression of glia markers in Line 61 and wild type mice. Immunofluorescent labeling patterns of neuroinflammation markers in 6 and 9-months old mice. Magnified single channel images show human α-Syn immunoreactivity (red channel; note absence of signal in wild type mice), IBA1 (microglia white), GFAP (astrocytes green), and DAPI (blue). The general labeling pattern of the gliosis markers is similar in either genotype. CX cortex, HC hippocampus, sl stratum lucidum, so stratum oriens, sp stratum pyramidale, sr stratum radiatum. Scale bar A, F, K, P 500 µm; grey images: 50 µm