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Fig. 3 | BMC Neuroscience

Fig. 3

From: Effectiveness of conservative interventions for sickness and pain behaviors induced by a high repetition high force upper extremity task

Fig. 3

Inflammatory cytokine immunoreactivity in brain ependymal and endothelial cells. A–C There was an absence of IL-1beta and TNFalpha in these cell types in FRC rat brains. D–F IL-1beta and TNFalpha immunoreactivity increased in these cell types in 12-week HRHF rats. In D and E, arrows indicate positively stained ependymal cells surrounding the ventricle as well as small stained glial-like cells within the brain parenchyma. In F, inset shows IL-1beta stained endothelial cell. G, H Percent area with IL-1beta and TNFalpha immunoreactivity, respectively, in ependymal cells. Results for one-way ANOVAs are shown. **p < 0.01, compared to FRC rats; †p < 0.05, compared to untreated HRHF rats

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