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Fig. 1 | BMC Neuroscience

Fig. 1

From: The loss-of-function disease-mutation G301R in the Na+/K+-ATPase α2 isoform decreases lesion volume and improves functional outcome after acute spinal cord injury in mice

Fig. 1

α2 isoform levels are reduced in α +/G301R2 compared to α +/+2 mice under naïve conditions. a Western blotting analysis showed comparable levels of α1 and α3, but reduced levels of α2 protein in the spinal cord of α +/G301R2 compared to α +/+2 mice under naïve conditions. b Quantification of α1, α2 and α3 isoform levels compared to GAPDH levels (Tukey’s multiple comparisons test; n.s (p = 0.99) for α1, **p < 0.01 (p = 0.0028) for α2 and n.s p = 0.99) for α3 (n = 4 mice/group). c Immunofluorescent staining of α2 (green) in a thoracic spinal cord section from naïve α +/G301R2 mice co-stained with the neuronal marker NeuN (red, arrows). Scale bar 50 μm

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BMC Neuroscience

ISSN: 1471-2202

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