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Fig. 3 | BMC Neuroscience

Fig. 3

From: PPARγ coactivator-1α (PGC-1α) protects neuroblastoma cells against amyloid-beta (Aβ) induced cell death and neuroinflammation via NF-κB pathway

Fig. 3

Effects of PGC-1α on Aβ1–42 induced neuroinflammation. N2a cells transfected with an empty vector or PGC-1α overexpression plasmid were treated with or without Aβ1–42 (25 μM) for 6 h. Culture media was collected and subjected to ELISA for a TNF-α and b IL-1β. Results shown represent the mean ± SEM (two-way ANOVA with Bonferroni post-tests) for three independent experiments. ***p < 0.001 compared to control group

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