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Fig. 1 | BMC Neuroscience

Fig. 1

From: A gradient of frequency-dependent synaptic properties along the longitudinal hippocampal axis

Fig. 1

Examples of synaptic responses (fEPSPs) evoked by a stimulation train of ten pulses delivered at different representative frequencies are shown for three representative slice positions along the dorsoventral axis of the hippocampus. Records were obtained from three slices located 1, 6 and 9.5 mm along the dorsoventral axis of the hippocampus, corresponding to the most dorsal (DORSAL), medial (MEDIAL) and most ventral part (VENTRAL) of the hippocampus. Baseline fEPSPs in the three slices had similar amplitude (~ 1.5 mV). Note that the steady-state response in the dorsal slice was facilitation for most stimulation frequencies (1–40 Hz) and only at 100 Hz showed a moderate depression. In sharp contrast, the response of the ventral hippocampal slice was depression for all stimulus frequencies. The responses evoked in the medial hippocampus slice were intermediate between those recorded from the dorsal and the ventral slice

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