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Fig. 3 | BMC Neuroscience

Fig. 3

From: Metabolomics analysis of serum in a rat heroin self-administration model undergoing reinforcement based on 1H-nuclear magnetic resonance spectra

Fig. 3

OPLS-DA score plot (a) and corresponding coefficient plot (b) derived from the 1H NMR spectra of extractions of serum obtained from control group (n = 8) and SA group (n = 7). A correlation coefficient of |r| > 0.707 (df = 6) was used as the cut-off value that gave a statistically significant result at the level p < 0.05. The loading maps show the significance of metabolite variations between two classes. Peaks in the positive and negative direction indicate the metabolites that are more abundant in SA group and in the control group respectively

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