Fig. 9From: RETRACTED ARTICLE: Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s diseaseCur and SLCP treatments reduce neuroinflammation in CA1 subfield of hippocampus in 5xFAD mice. The 5xFAD mice were treated with Cur or SLCP for 2- or 5-days, sacrificed, and their brain sections were collected and immunolabeled for Iba-1 and GFAP. The number of labeled Iba-1-IR (a, b) and GFAP-IR (a, c) cells were significantly reduced (*p < 0.05; **p < 0.01) in the CA1 area, in comparison to vehicle-treated 5xFAD mice, with further reductions were observed after 5 days of treatment, compared with that of at 2 days (b, c). Scale bar indicates 250 µm and is applicable to other imagesBack to article page