Fig. 6

Quantitative digital histology image analysis. The high-resolution digital histology images represent the motor cortex subcortical white matter stained for PLP and grey matter stained for CD68, ferritin and pTDP-43 in ALS. Colour deconvolution for positive staining (brown) generates markup images demonstrating unstained pixels = white, negative stained pixels = blue, weak positive pixels = yellow, medium positive pixels = orange and strong positive pixels = red. Scale bar = 100 μm