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Fig. 1 | BMC Neuroscience

Fig. 1

From: Delayed and repeated intranasal delivery of bone marrow stromal cells increases regeneration and functional recovery after ischemic stroke in mice

Fig. 1

Experimental timeline. Focal ischemic stroke was induced in adult male mice on “day 0”. Three days after stroke, a total volume of 100 μl of BMSC suspension (~ 1 × 106 cells) or control media was administered via the intranasal route at 3, 4, 5, and 6 days after stroke. Starting on the same day as BMSC administration, all mice received daily BrdU injections intraperitoneally (i.p) until the day of euthanasia. Laser-Doppler scanning was performed 21 days after stroke to measure changes in the local blood flow in penumbra. The adhesive removal test of sensorimotor function was performed at 7 and 14 days after stroke. Immunohistochemistry was performed at 14 days after stroke to analyze regeneration

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BMC Neuroscience

ISSN: 1471-2202

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