Fig. 3From: Delayed and repeated intranasal delivery of bone marrow stromal cells increases regeneration and functional recovery after ischemic stroke in miceHypoxic-preconditioning increases survival factors in BMSCs. BMSCs were subjected to 24 h hypoxic preconditioning (0.1–0.3% oxygen) and 1 h of reoxygenation. RT-PCR analysis was used to detect the mRNA level of two key genes for cell survival, HIF-1α and Bcl-xL. a HIF-1α in HP-BMSCs was increased compared to control BMSCs. N = 3, p = 0.013; student’s t test. b Increased Bcl-xL after HP treatment compared to control BMSCs. N = 3, *p < 0.05, student’s t testBack to article page