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Table 1 Clinical and biochemical characteristics of 30-day surviving and non-surviving patients with spontaneous intracerebral hemorrhage (SIH)

From: Association between serum levels of caspase-cleaved cytokeratin-18 and early mortality in patients with severe spontaneous intracerebral hemorrhage

 

Survivors

(n = 54)

Non-survivors

(n = 46)

P value

Gender female—n (%)

17 (31.5)

17 (37.0)

0.67

Site of SIH—n (%)

  

0.81

 Lobar

41 (75.9)

33 (71.7)

 

 Basal ganglia

3 (5.6)

4 (8.7)

 

 Thalamus

5 (9.3)

3 (6.5)

 

 Periventricular

5 (9.3)

6 (13.0)

 

Cause of SIH—n (%)

  

0.07

 Hypertension

37 (68.5)

30 (65.2)

 

 Amyloid angiopathy

2 (3.7)

4 (8.7)

 

 Aneurysm

3 (5.6)

0

 

 Arteriovenous malformation

5 (9.3)

0

 

 OAT in therapeutic range

3 (5.6)

6 (13.0)

 

 OAT out of therapeutic range

3 (5.6)

6 (13.0)

 

 Fibrinolytic treatment

1 (1.9)

0

 

Intraventricular hemorrhage—n (%)

17 (31.5)

23 (50.0)

0.07

Hydrocephalus—n (%)

21 (38.9)

26 (56.5)

0.11

Evacuation SIH—n (%)

18 (33.3)

9 (19.6)

0.18

Age (years)—median (p 25–75)

59 (52–67)

68 (57–74)

0.006

Volume of SIH (cc)—median (p 25–75)

38 (17–62)

68 (29–99)

0.02

Midline shift (mm)—median (p 25–75)

1 (0–7)

5 (0–11)

0.005

Sodium (mEq/L)—median (p 25–75)

139 (137–142)

139 (135–143)

0.93

Temperature (°C)—median (p 25–75)

36.9 (36.0–37.4)

36.5 (35.0–37.0)

0.10

PaO2/FI02 ratio—median (p 25–75)

270 (189–350)

289 (215–397)

0.40

Platelets—median*103/mm3 (p 25–75)

193 (145–252)

198 (159–270)

0.57

INR—median (p 25–75)

1.10 (1.00–1.31)

1.14 (1.02–1.87)

0.34

Lactic acid (mmol/L)-median (p 25–75)

1.70 (1.00–2.51)

1.80 (1.30–2.55)

0.23

GCS score—median (p 25–75)

8 (6–8)

4 (3–6)

< 0.001

Glycemia (g/dL)—median (p 25–75)

141 (118–190)

170 (141–216)

0.01

aPTT (s)—median (p 25–75)

29 (27–32)

30 (24–34)

0.68

Fibrinogen (mg/dl)—median (p 25–75)

390 (280–493)

382 (350–510)

0.34

APACHE-II score—median (p 25–75)

18 (14–20)

24 (20–26)

<0.001

Creatinine (mg/dl)—median (p 25–75)

0.77 (0.68–0.90)

0.80 (0.60–1.01)

0.36

CCCK-18 (u/L)—median (p 25–75)

129 (112–177)

291 (212–341)

< 0.001

  1. P 25–75 25th–75th percentile, OAT oral anticoagulant treatment, PaO 2 pressure of arterial oxygen/fraction inspired oxygen, FIO 2 pressure of arterial oxygen/fraction inspired oxygen, INR international normalized ratio, GCS Glasgow Coma Scale, aPTT activated partial thromboplastin time, APACHE II Acute Physiology and Chronic Health Evaluation, CCCK caspase-cleaved cytokeratin