Fig. 1From: Differential modulation of human GABAC-ρ1 receptor by sulfur-containing compounds structurally related to taurineActivation by GABA and SCC-tau of GABA-ρ1R heterologously expressed in oocytes. a Control: oocyte exposed to GABA at several concentrations (3–1000 µM); b–d Oocytes perfused with SCC-tau at the concentrations indicated. In each experiment the oocyte was first exposed to a GABA concentration equal to GABA’s EC50. The horizontal bars indicate the period of time when the compound was applicated. Oocytes were voltage-clamped at − 60 mV and inward currents are denoted as downward deflections. Chemical structure of GABA (a) and SCC-tau (b–d), are represent at right of each representative traceBack to article page