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Fig. 3 | BMC Neuroscience

Fig. 3

From: Involvement of Akt/CREB signaling pathways in the protective effect of EPA against interleukin-1β-induced cytotoxicity and BDNF down-regulation in cultured rat hippocampal neurons

Fig. 3

The effect of EPA on Akt and CREB phosphorylation was blocked by inhibition of the Akt signal, in the presence of IL-1β in cultured rat hippocampal neurons. a Cells pretreated with KRX-0401 and then treated with EPA and IL-1β, and the proteins expression was measured by western blotting. b Relative levels of proteins were determined by densitometry of the immunoblots. Data were normalized by taking the value of the control group as 1. **P < 0.01 versus control group; ##P < 0.01 versus IL-1β group

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BMC Neuroscience

ISSN: 1471-2202

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