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Fig. 4 | BMC Neuroscience

Fig. 4

From: Involvement of Akt/CREB signaling pathways in the protective effect of EPA against interleukin-1β-induced cytotoxicity and BDNF down-regulation in cultured rat hippocampal neurons

Fig. 4

EPA reversed the inhibitory effects of IL-1β on the expression of BDNF via the Akt/CREB pathways in cultured rat hippocampal neurons. a BDNF mRNA and protein, b expression were measured by real-time PCR and western blotting, respectively. c Relative levels of BDNF protein were determined by densitometry of the immunoblots. Data from PCR and western blotting were normalized by taking the value of the control group as 1. **P < 0.01 versus control group; ##P < 0.01 versus IL-1β group

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BMC Neuroscience

ISSN: 1471-2202

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