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Fig. 4 | BMC Neuroscience

Fig. 4

From: Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla 1H-MRS study

Fig. 4

T2-weighted magnetic resonance imaging (MRI) of a mice brain after controlled cortical impact (CCI). Representative coronal images of cortical contusion show that the ipsilateral cortical edema was visible 24 h after injury, as a diffuse tissue hyperintensity (red arrows), and brain swelling was indicated by a midline shift (blue arrow). The extent of both cortical edema and brain swelling in KO + CCI mice was lower than that in WT + CCI mice. The water-content of the contralateral cerebral hemisphere was low and was similar in all groups (p > 0.05). Moreover, the KO + CCI group had a significantly lower brain water-content than did the WT + CCI group (#p < 0.05)

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